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    Hong yang pittsburgh

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    J Cell Sci. CBMP Faculty. Development Accomplishing the specific aims in this proposal will establish the regulation of AJ dynamics as a key molecular and cellular mechanism by which Sdt, Crb and Lgl to control the apical-basal polarization in epithelial cells. Differential regulation of adherens junction dynamics during apical-basal polarization. To test this hypothesis, we have developed a novel genomic engineering approach in Drosophila that enables us to modify a target gene into any desired mutant alleles.

  • University of Pittsburgh Department of Cell Biology
  • Regulation of Adherens Junction Trafficking by Polarity Proteins Yang Hong
  • Pi, Hongyang MD Forbes Ave Pittsburgh, PA Doctors MapQuest

  • Yang Hong, Ph.D. Associate Professor Tel: Fax: Address: S BST-South [email protected] CBP Research Group(s). Yang Hong, Ph.D. Image - Yang Hong.

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    Title: Associate Professor Department: Dept of Cell Biology Email: [email protected] PubMed: Link Dept / Lab Webpage. Yang Hong of University of Pittsburgh, PA (Pitt) | Read 61 publications, and contact Yang Hong on ResearchGate, the professional network for scientists.
    Establishing and maintaining apical-basal polarity is crucial for the function and structure of epithelia, while disruption of such polarity often accompanies the malignant transformation or stress-induced damage of epithelial cells.

    Epub May 8. Lab Website. Yang Hong, Ph. Name University of Pittsburgh.

    images hong yang pittsburgh
    GALAXY I9000 CYANOGENMOD 10.2
    Cell Res. J Genet Genomics J Cell Biol J Cell Biol.

    University of Pittsburgh Department of Cell Biology

    Research in my lab focuses on the molecular mechanisms regulating the cell polarity.

    View Yang Hong's profile on LinkedIn, the world's largest professional community. Yang has 2 jobs listed on their profile. See the complete profile on LinkedIn. Yang Hong.

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    Software Engineer at UPMC Technology Development Center. Pittsburgh, Pennsylvania. Computer Software.

    Regulation of Adherens Junction Trafficking by Polarity Proteins Yang Hong

    UPMC Technology Development. ~yang. Country Employment. Source: Yee Hong Yang.

    Pi, Hongyang MD Forbes Ave Pittsburgh, PA Doctors MapQuest

    Preferred Mellon Institute: Pittsburgh, PA. to.
    J Genet Genomics Fly Austin. J Cell Biol.

    Video: Hong yang pittsburgh Hong Yang 楊泓 (雷霆太極) Sun style Tai Chi 73 form

    Here we propose that control of adherens junction AJ dynamics by polarity proteins Stardust SdtCrumbs Crb and Lethal giant larvae Lgl is an essential cellular mechanism for establishing apical-basal polarity. Accomplishing the specific aims in this proposal will establish the regulation of AJ dynamics as a key molecular and cellular mechanism by which Sdt, Crb and Lgl to control the apical-basal polarization in epithelial cells.

    images hong yang pittsburgh

    The ongoing projects focus on: 1 Mechanisms regulating the polarized membrane targeting of polarity proteins : Direct binding between Lgl and plasma membrane would localize Lgl to both apical and basolateral membrane domain, rather than exclusively to the basolateral domains.

    Epub Feb

    images hong yang pittsburgh
    Hong yang pittsburgh
    Epub Apr The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded.

    Related projects. J Cell Sci A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia. Using both Drosophila and cultured mammalian cells as model systems, we are investigating how direct interactions between polarity proteins and plasma membrane lipids may act as a crucial molecular mechanism regulating the subcellular localizations and functions of polarity proteins.

    Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

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